Blar i forfatter "Uhlig, Silvio"

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    • Characterization and pro-inflammatory responses of spore and hyphae samples from various mold species 

      Øya, Elisabeth; Afanou, Komlavi Anani; Malla, Nabin; Uhlig, Silvio; Rolen, Elin; Skaar, Ida; Straumfors, Anne; Winberg, Jan-Olof; Bang, Berit; Schwarze, Per E; Eduard, Wijnand; Holme, Jørn Andreas (Journal article; Tidsskriftartikkel; Manuskript; Peer reviewed; Preprint, 2017-09-18)
      Mold particles from <i>Aspergillus fumigatus, Penicillium chrysogenum, Aspergillus versicolor</i>, and <i>Stachybotrys chartarum</i> have been linked to respiratory‐related diseases. We characterized X‐ray‐inactivated spores and hyphae fragments from these species by number of particles, morphology, and mycotoxin, β‐glucan and protease content/activity. The pro‐inflammatory properties of mold particles ...

    • Fish Skin and Gill Mucus: A Source of Metabolites for Non-Invasive Health Monitoring and Research 

      Ivanova, Lada; Rangel-Huerta, Oscar Daniel; Tartor, Haitham; Gjessing, Mona Cecilie; Dahle, Maria; Uhlig, Silvio (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-31)
      Mucous membranes such as the gill and skin mucosa in fish protect them against a multitude of environmental factors. At the same time, changes in the molecular composition of mucus may provide valuable information about the interaction of the fish with their environment, as well as their health and welfare. In this study, the metabolite profiles of the plasma, skin and gill mucus of freshwater ...

    • Pharmacokinetics of a long-acting subcutaneous eprinomectin injection in semi-domesticated reindeer (Rangifer tarandus tarandus) - a pilot study 

      Davidson, Rebecca K.; Fæste, Christiane Kruse; Uhlig, Silvio; Tukun, Feng-Ling; Lian, Hans Edvin; Solvang, Hans Arne; Thorvaldsen, Renate; Folkow, Lars; Sanchez Romano, Javier; Kilvær, Marianne V.; Holmgren, Karin Elisabeth; Nymo, Ingebjørg Helena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-17)
      Reindeer (Rangifer tarandus tarandus) are exposed to the pathogenic parasitic nematode Elaphostrongylus rangiferi during grazing. The severity of disease is dose-dependent. Prophylactic anthelmintic treatment is needed to improve animal health and reindeer herding sustainability. Herds are traditionally only gathered once during the summer, requiring a drug with a persistent effect. In this study ...

    • Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ 

      Moldes-Anaya, Angel; Sæther, Thomas; Uhlig, Silvio; Nebb, Hilde Irene; Larsen, Terje; Eilertsen, Hans Christian; Paulsen, Steinar Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-25)
      The peroxisome proliferator-activated receptors (PPARs) function as ligand-activated transcription factors that convert signals in the form of lipids to physiological responses through the activation of metabolic target genes. Due to their key roles in lipid and carbohydrate metabolism, the PPARs are important drug targets. However, for several of the PPAR drugs currently in use, adverse side effects ...